Article
Redefining Macrophage Heterogeneity in Atherosclerosis: A Focus on Possible Therapeutic Implications
19 Mar 2025
Abstract excerpt
ABSTRACT Atherosclerosis is a lipid disorder where modified lipids (especially oxidized LDL) induce macrophage foam cell formation in the aorta. Its pathogenesis involves a continuum of persistent inflammation accompanied by dysregulated anti‐inflammatory responses. Changes in the immune cell status due to differences in the lesional microenvironment are crucial in terms of plaque development, its progression,...
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