Article
Human monocyte-derived macrophages spontaneously differentiated in vitro show distinct phenotypes.
Journal of cellular physiology - 1 Jul 2013
Eligini Sonia, Crisci Mauro, Bono Elisa, Songia Paola, Tremoli Elena, Colombo Gualtiero I, Colli Susanna
Abstract excerpt
Tissue macrophages are resident phagocytes that acquire specific phenotypes according to the microenvironment. Morphological and functional heterogeneity has been evidenced in different homeostatic and pathological conditions. Indeed, the nature of macrophage subsets may have either harmful or beneficial functions in disease progression/resolution. Therefore the possibility to pharmacologically manipulate...
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