Article
Association of MUC16 Mutation With Response to Immune Checkpoint Inhibitors in Solid Tumors.
JAMA network open - 3 Aug 2020
Zhang Lei, Han Xiaohong, Shi Yuankai
Abstract excerpt
Importance: As the third most frequently mutated gene in cancers, the association between MUC16 mutation and response to immune checkpoint inhibitors (ICIs) in solid tumors remains unclear. Objective: To examine whether MUC16 mutation is associated with genomic factors in ICI response in solid tumors and with outcomes in ICI-treated patients. Design, Setting, and Participants: This cohort study used...
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