Article
Comprehensive characterization of MUC16 mutations in lung adenocarcinoma for immunotherapies and prognosis: An observational study.
Medicine - 3 Nov 2023
Liu Tingjun, Wu Lianlian, Liu Jing, Chen Hao, Zhu Bao, Qiao Dandan, Zhu Yuhua, Liu Tingya, Chen Quangang, Hu Ankang
Abstract excerpt
Lung adenocarcinoma (LUAD) is a non-small-cell lung cancer and is the leading cause of cancer-related deaths worldwide. Immunotherapy is a promising candidate for LUAD, and tumor mutation burden (TMB) could be a new biomarker to monitor the response of cancer patients to immunotherapy. It is known that the mucin 16 (MUC16) mutation is the most common and affects the progression and prognosis of several cancers....
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