Article
Identification of microRNA associated with the elimination of hepatitis C virus genotype 1b by direct-acting antiviral therapies.
Journal of gastroenterology and hepatology - 1 Apr 2021
Yoneyama Hirohito, Morishita Asahiro, Iwama Hisakazu, Fujita Koji, Masaki Takahiro, Tani Joji, Tadokoro Tomoko, Nomura Takako, Sakamoto Teppei, Oura Kyoko, Takuma Kei, Nakahara Mai, Mimura Shima, Deguchi Akihiro, Oryu Makoto, Tsutsui Kunihiko, Himoto Takashi, Shimotohno Kunitada, Wakita Takaji, Kobara Hideki, Masaki Tsutomu
Abstract excerpt
BACKGROUND AND AIM: Direct-acting antiviral (DAA) therapies have been proven to be highly effective for the eradication of hepatitis C virus (HCV) without resistance-associated substitutions (RASs). However, even in cases with no detected RASs, treatment sometimes fails, suggestive of the existence of some host-related factors involved in HCV eradication by DAAs. To explore such factors, we analyzed the serum...
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