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Article

Characterization of microRNA expression profiles associated with hepatitis B virus replication and clearance in vivo and in vitro

18 Nov 2011

Abstract excerpt

BACKGROUND AND AIM: Alpha interferon (IFN-α) is an approved treatment for chronic hepatitis B (CHB). MicroRNA (miRNA) are currently known as a part of IFN-mediated antiviral defense. We aimed at characterizing the miRNA expression associated with hepatitis B virus (HBV) replication and IFN-mediated HBV clearance. METHODS: We investigated the expression patterns of cellular miRNA induced by HBV replication and/or...

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PMID: 22097931
DOI: 10.1111/j.1440-1746.2011.06979.x

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