Article
Serum interferon-related microRNAs as biomarkers to predict the response to interferon therapy in chronic hepatitis C genotype 4.
PloS one - 1 Jan 2015
Motawi Tarek Kamal, Shaker Olfat Gamil, El-Maraghy Shohda Assem, Senousy Mahmoud Ahmed
Abstract excerpt
MicroRNAs are messengers during interferon-virus interplay and are involved in antiviral immunity, however, little is known about interferon-related microRNAs regarding their detection in serum and their potential use as non-invasive diagnostic and prognostic biomarkers in chronic hepatitis C (CHC). To elucidate some of the molecular aspects underlying failure of pegylated interferon-α/ribavirin therapy, we...
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