Article
Circulating microRNAs as predictors of response to sofosbuvir + daclatasvir + ribavirin in in HCV genotype-4 Egyptian patients.
BMC gastroenterology - 3 Dec 2022
Hassuna Noha Anwar, Gamil Aya Nabil, Mahmoud Mahmoud Shokry, Mohamed Wafaa Khairy, Khairy Rasha
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs) play an important role in various diseases, including HCV infection, the aim of the current study was to evaluate the potential use of serum miRNAs as biomarkers for diagnosis, prognosis, and prediction of responses to direct acting antivirals (sofosbuvir + daclatasvir + ribavirin) in HCV-4 patients. METHODS: The serum expression profiles of four liver-associated miRNAs (miRNA-122,...
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