Article

Chronic Pulmonary Aspergillosis: Genomic Variant Analysis and Protein Dysfunction Susceptibility in a Brazilian Cohort

2025-04-21

Abstract excerpt

<title>Abstract</title> <p>Chronic pulmonary aspergillosis (CPA) is a debilitating condition often affecting immunocompetent patients with underlying structural lung diseases, particularly pulmonary tuberculosis. This study investigates single nucleotide variants (SNVs) in immunogenetic-related genes among a Brazilian cohort with CPA. Twelve patients with confirmed CPA, based on ESCMID/ERS criteria, were sequence...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: de6d1680-b4d7-58d7-8141-28c07baf5f28
DOI: 10.21203/rs.3.rs-6473313/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Chronic Pulmonary Aspergillosis: Genomic Variant Analysis and Protein Dysfunction Susceptibility in a Brazilian CohortDOI 10.21203/rs.3.rs-6473313/v1Read

Chronic Pulmonary Aspergillosis: Genomic Variant Analysis and Protein Dysfunction Susceptibility in a Brazilian CohortSemantic proximity Read

Genetic background and immune response in paracoccidioidomycosis: A systematic review and meta-analysis of single nucleotide variants.Semantic proximity Read

Pharmacogenetics and Theratyping in Pulmonology: A Practical GuideSemantic proximity Read

Genetic and transcriptomic determinants of disseminated coccidioidomycosis identify a founder variant in <i>NLRX1</i> and ancestry-specific rare variants in immune response genesSemantic proximity Read

Deciphering the Genetic Architecture of Chronic Obstructive Pulmonary Disease (COPD): Insights from the UK Biobank and Mendelian Randomization AnalysisSemantic proximity Read

Clinical, biochemical, and genetic characterization of Lebanese patients with chronic granulomatous disease due to NCF2 pathogenic variants.Semantic proximity Read

Assessing pathogenicity: overview of results from the IARC Unclassified Genetic Variants Working GroupSemantic proximity Read

Polymorphisms in Innate and Adaptive Immune Genes in Subjects with Allergic Bronchopulmonary Aspergillosis Complicating Asthma.Semantic proximity Read

Polymorphisms within the ARNT2 and CX3CR1 Genes Are Associated with the Risk of Developing Invasive Aspergillosis.Semantic proximity Read

Genome-wide association analyses of common infections in a large practice-based biobank.Semantic proximity Read

Genetic susceptibility to allergic bronchopulmonary aspergillosis in asthma: a genetic association studySemantic proximity Read