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Article

The Role of Immune Infiltration and Oxidative Stress in the Progression of Cerebral Cavernous Malformation.

Brain and behavior - 1 Feb 2026

Zhu Xuesai, Yao Yizhi, Yu Tengbo, Xiao Xiao

Abstract excerpt

PURPOSE OF REVIEW: To review how the immune microenvironment and oxidative stress modulate the initiation, maturation, and hemorrhagic conversion of cerebral cavernous malformations (CCM) and to appraise the therapeutic potential of immune-directed interventions. FINDING: This project conducts systematic research on the pathogenesis of cerebral cavernous malformation (CCM), focusing on the complex interactions...

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Source

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Identifiers

PMID: 41618979
DOI: 10.1002/brb3.71237
PMCID: PMC12860402

Genes

CCM2
PDCD10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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