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rs2274911 polymorphism in GPRC6A associated with serum E2 and PSA in a Southern Chinese male population.

Gene - 30 Dec 2020

Qi Nana, Chen Yang, Zeng Yanyu, Bao Mengying, Long Xinyang, Guo Yajie, Tan Aihua, Gao Yong, Zhang Haiying, Yang Xiaobo, Hu Yanling, Mo Zengnan, Jiang Yonghua

Abstract excerpt

BACKGROUND: rs2274911 (Pro91Ser, G > A) is a missense mutation located on the second exon of the GPRC6A gene. Increasing evidence revealed a significant association between the A allele of rs2274911 and male diseases, such as oligospermia, cryptorchidism, and prostate tumor. However, the function of rs2274911 in healthy males is unclear. SUBJECTS AND METHODS: A total of 1742 healthy men were selected from the...

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PMID: 32827681
DOI: 10.1016/j.gene.2020.145067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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