Article

Identification of a novel ESR1 mutation in a Chinese PCOS woman with estrogen insensitivity in IVF treatment

2022-09-02

Abstract excerpt

<h4>Background: </h4> Polycystic ovary syndrome (PCOS) is a complex reproductive disorder, affecting approximately 5-10% of women of reproductive age. The complexity of the disease is contributed by genetic, lifestyle and environmental factors. Previous studies emphasized the important roles of estrogen receptors played in the pathogenesis of PCOS. <h4>Objective: </h4> To assess the possible pathogenic factors of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 332329fd-1d58-5934-9b0a-890920df204f
DOI: 10.21203/rs.3.rs-2015805/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of a novel ESR1 mutation in a Chinese PCOS woman with estrogen insensitivity in IVF treatmentDOI 10.21203/rs.3.rs-2015805/v1Read

Identification of a novel ESR1 mutation in a Chinese PCOS woman with estrogen insensitivity in IVF treatment.Semantic proximity Read

Exploring the association of ESR1 and ESR2 gene SNPs with polycystic ovary syndrome in human females: a comprehensive association study.Semantic proximity Read

Biochemical Characterization and Molecular Determination of Estrogen Receptor-α (ESR1 PvuII-rs2234693 T>C) and MiRNA-146a (rs2910164 C>G) Polymorphic Gene Variations and Their Association with the Risk of Polycystic Ovary SyndromeSemantic proximity Read

Association of estrogen receptor gene variants (ESR1 and ESR2) with polycystic ovary syndrome in Tunisia.Semantic proximity Read

Human Cancers Deriving from Either Genetic or Lifestyle Factors, Are Initiated by the Damage of Estrogen SignalingSemantic proximity Read

Familial Multiplicity of Estrogen Insensitivity Associated With a Loss-of-Function ESR1 Mutation.Semantic proximity Read

ESR1 Mutations Associated With Estrogen Insensitivity Syndrome Change Conformation of Ligand-Receptor Complex and Altered Transcriptome ProfileSemantic proximity Read

Variant Alleles of the ESR1, PPARG, HMGA2, and MTHFR Genes Are Associated With Polycystic Ovary Syndrome Risk in a Chinese Population: A Case-Control StudySemantic proximity Read

A Novel Compound Heterozygous Mutation of FSHR Causes Primary Ovarian InsufficiencySemantic proximity Read

A Novel Homozygous Missense FSHR Variant Associated with Hypergonadotropic Hypogonadism in Two Siblings from a Brazilian FamilySemantic proximity Read

A genome-wide association study of early menopause and the combined impact of identified variants.Semantic proximity Read

Perspectives in Polycystic Ovary Syndrome: From Hair to Eternity.Semantic proximity Read