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Article

Genetic Analysis of 25 Patients with 5α-Reductase Deficiency in Chinese Population.

BioMed research international - 1 Jan 2020

Han Bing, Cheng Tong, Zhu Hui, Yu Jie, Zhu Wen-Jiao, Song Huai-Dong, Yao Haijun, Qiao Jie

Abstract excerpt

BACKGROUND: A deficiency in steroid 5α-reductase type 2 is an autosomal recessive disorder. Affected individuals manifested ambiguous genitalia, which is caused by decreased dihydrotestosterone (DHT) synthesis in the fetus. METHODS: We analyzed 25 patients with 5α-reductase deficiency in China. Seventeen of the 25 patients (68%) were initially raised as females. Sixteen patients changed their social gender from...

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Identifiers

PMID: 32596280
DOI: 10.1155/2020/1789514
PMCID: PMC7301183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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