Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of novel GRM1 mutations and single nucleotide polymorphisms in prostate cancer cell lines and tissues.

PloS one - 1 Jan 2014

Ali Shafat, Shourideh Mojgan, Koochekpour Shahriar

Abstract excerpt

Metabotropic glutamate receptor 1 (GRM1) signaling has been implicated in benign and malignant disorders including prostate cancer (PCa). To further explore the role of genetic alterations of GRM1 in PCa, we screened the entire human GRM1 gene including coding sequence, exon-intron junctions, and flanking untranslated regions (UTRs) for the presence of mutations and single nucleotide polymorphisms (SNPs) in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Epithelial Cells
Share to Introns

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation, Missense

Share to Prostatic Neoplasms

Share to Receptors, Metabotropic Glutamate

Share to Untranslated Regions

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 25062106
DOI: 10.1371/journal.pone.0103204
PMCID: PMC4111546

Genes

GRM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of novel GRM1 mutations and single nucleotide polymorphisms in prostate cancer cell lines and tissues.PMID 25062106Read ↗

Metabotropic glutamate receptor 1 expression and its polymorphic variants associate with breast cancer phenotypes.Semantic proximity Read ↗

Assessment of Single Nucleotide Variants in hGPRC5A Gene Using in-silico ToolsSemantic proximity Read ↗

rs2274911 polymorphism in GPRC6A associated with serum E2 and PSA in a Southern Chinese male population.Semantic proximity Read ↗

Allelic association, DNA resequencing and copy number variation at the metabotropic glutamate receptor GRM7 gene locus in bipolar disorder.Semantic proximity Read ↗

Association between lncrna PCGEM1 polymorphisms and prostate cancer risk.Semantic proximity Read ↗

Somatic mutations in GRM1 in cancer alter metabotropic glutamate receptor 1 intracellular localization and signaling.Semantic proximity Read ↗

Impact of GRM7 gene variations on glioblastoma risk in the Iranian population.Semantic proximity Read ↗

Rare-type mutations of MMAC1 tumor suppressor gene in human glioma cell lines and their tumors of origin.Semantic proximity Read ↗

Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.Semantic proximity Read ↗

Mechanistic Link Between Glyoxalase 1 Expression and Methylglyoxal-Induced Oncogenic Stress in Prostate CancerSemantic proximity Read ↗

MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines.Semantic proximity Read ↗

Human methionine synthase A2756G polymorphism increases susceptibility to prostate cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.