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Article

Ankyrin 3: genetic association with bipolar disorder and relevance to disease pathophysiology

1 Oct 2012

Abstract excerpt

Bipolar disorder (BD) is a multi-factorial disorder caused by genetic and environmental influences. It has a large genetic component, with heritability estimated between 59-93%. Recent genome-wide association studies (GWAS) using large BD patient populations have identified a number of genes with strong statistical evidence for association with susceptibility for BD. Among the most significant and replicated...

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PMID: 23025490
DOI: 10.1186/2045-5380-2-18

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