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Molecular Targets for the Treatment of Metastatic Colorectal Cancer

20 Aug 2020

Abstract excerpt

Over the past years, colorectal cancer (CRC) was subtyped according to its molecular and genetic characteristics, allowing the development of therapeutic strategies, based on predictive biomarkers. Biomarkers such as microsatellite instability (MSI), RAS and BRAF mutations, HER2 amplification or NTRK fusions represent major tools for personalized therapeutic strategies. Moreover, the routine implementation of...

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PMID: 32825275
DOI: 10.3390/cancers12092350

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