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Ongoing and evolving clinical trials enhancing future colorectal cancer treatment strategies.

Expert opinion on investigational drugs - 1 Mar 2022

Ros Javier, Saoudi Nadia, Salvà Francesc, Baraibar Iosune, Alonso Guzman, Tabernero Josep, Elez Elena

Abstract excerpt

INTRODUCTION: Molecular profiling has led to significantly longer survival in metastatic colorectal cancer (CRC) patients. Clinical guidelines recommend testing for KRAS/NRAS, BRAF, and MSI status, and over the last few years, several promising new biomarkers have also been identified. Circulating tumor DNA has reshaped the prognosis of localized CRC. These genomic findings can guide treatment management to...

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Identifiers

PMID: 35133234
DOI: 10.1080/13543784.2022.2040016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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