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Article

Prognostic and predictive molecular biomarkers in advanced colorectal cancer.

Pharmacology & therapeutics - 1 Aug 2022

Martelli Valentino, Pastorino Alessandro, Sobrero Alberto F

Abstract excerpt

The revolution of precision medicine has produced unprecedented seismic shifts in the treatment paradigm of advanced cancers. Among the major killers, colorectal cancer (CRC) is far behind the others. In fact, the great successes obtained in breast, NSCLC, melanoma, and genitourinary tract tumors have been observed only in fewer than 5 % metastatic colorectal cancer (mCRC): those with the mismatch repair...

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PMID: 35780916
DOI: 10.1016/j.pharmthera.2022.108239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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