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Significance of stress keratin expression in normal and diseased epithelia

4 Jan 2024

Abstract excerpt

, are deemed stress responsive as they are induced in keratinocytes of surface epithelia in response to environmental stressors, in skin disorders (e.g., psoriasis) and in carcinomas. Monitoring stress keratins is widely used to identify keratinocytes in an activated state. Here, we analyze single-cell transcriptomic data from healthy and diseased human skin to explore the properties of stress keratins. Relative...

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PMID: 38299111
DOI: 10.1016/j.isci.2024.108805

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