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Article

Unravelling the mechanism of pH-regulation in dinoflagellate luciferase.

International journal of biological macromolecules - 1 Dec 2020

Kamerlin Natasha, Delcey Mickaël G, Lindh Roland

Abstract excerpt

Dinoflagellates are the dominant source of bioluminescence in coastal waters. The luminescence reaction involves the oxidation of luciferin by a luciferase enzyme, which only takes place at low pH. The pH-dependence has previously been linked to four conserved histidines. It has been suggested that their protonation might induce a conformational change in the enzyme, thereby allowing substrate access to the...

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Identifiers

PMID: 32822730
DOI: 10.1016/j.ijbiomac.2020.08.071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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