Article
The integration of transcriptome-wide association study and mRNA expression profiling data to identify candidate genes and gene sets associated with dental caries.
Archives of oral biology - 1 Oct 2020
Tong Xiangyao, Hou Siyu, Ma Mei, Zhang Lu, Zou Rui, Hou Tiezhou, Niu Lin
Abstract excerpt
OBJECTIVE: The aim of this study was to identify candidate genes and gene sets associated with dental caries by an integrative analysis of transcriptome-wide association study (TWAS) and messenger RNA (mRNA) expression profiling of dental caries. METHODS: A genome-wide association study (GWAS) dataset of dental caries was obtained from the UK Biobank. A TWAS of dental caries was conducted with the FUSION tool...
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