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Deep Saliva Proteomics Elucidating the Pathogenesis of Early Childhood Caries and Identifying Biomarkers for Early Prediction

16 Dec 2024

Abstract excerpt

Early childhood caries (ECC) significantly impacts the physical and mental health of children. Saliva stands as a critical model for investigating the pathogenesis of caries disease since it reflects both host and microbial dynamics. However, the specific contributions of salivary host factors to ECC have not been fully understood. In this study, we monitored a prospective cohort of 3-4 year-old healthy children...

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PMID: 39681551
DOI: 10.1021/acs.jproteome.4c00831

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