Article
Novel caries loci in children and adults implicated by genome-wide analysis of families.
BMC oral health - 1 Jun 2018
Govil Manika, Mukhopadhyay Nandita, Weeks Daniel E, Feingold Eleanor, Shaffer John R, Levy Steven M, Vieira Alexandre R, Slayton Rebecca L, McNeil Daniel W, Weyant Robert J, Crout Richard J, Marazita Mary L
Abstract excerpt
BACKGROUND: Dental caries is a common chronic disease among children and adults alike, posing a substantial health burden. Caries is affected by multiple genetic and environmental factors, and prior studies have found that a substantial proportion of caries susceptibility is genetically inherited. METHODS: To identify such genetic factors, we conducted a genome-wide linkage scan in 464 extended families with 2616...
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