Article
Genome-wide association scan for childhood caries implicates novel genes.
Journal of dental research - 1 Dec 2011
Shaffer J R, Wang X, Feingold E, Lee M, Begum F, Weeks D E, Cuenco K T, Barmada M M, Wendell S K, Crosslin D R, Laurie C C, Doheny K F, Pugh E W, Zhang Q, Feenstra B, Geller F, Boyd H A, Zhang H, Melbye M, Murray J C, Weyant R J, Crout R, McNeil D W, Levy S M, Slayton R L, Willing M C, Broffitt B, Vieira A R, Marazita M L
Abstract excerpt
Dental caries is the most common chronic disease in children and a major public health concern due to its increasing incidence, serious health and social co-morbidities, and socio-demographic disparities in disease burden. We performed the first genome-wide association scan for dental caries to identify associated genetic loci and nominate candidate genes affecting tooth decay in 1305 US children ages 3-12 yrs....
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