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Article

Natural Variation in Clinical Isolates of Candida albicans Modulates Neutrophil Responses.

mSphere - 19 Aug 2020

Shankar Madhu, Lo Tricia L, Traven Ana

Abstract excerpt

Neutropenia predisposes patients to life-threatening infection with Candida albicans, a commensal and opportunistic fungal pathogen. How phenotypic variation in C. albicans isolates dictates neutrophil responses is poorly understood. By using a panel of clinical C. albicans strains, here we report that the prototype strain SC5314 induces the most potent accumulation of reactive oxygen species (ROS) and neutrophil...

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Identifiers

PMID: 32817378
DOI: 10.1128/mSphere.00501-20
PMCID: PMC7440844

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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