Article
Conserved Inhibition of Neutrophil Extracellular Trap Release by Clinical Candida albicans Biofilms
6 Sept 2017
Abstract excerpt
Candida albicans biofilms are difficult to eradicate due to their resistance to host defenses and antifungal drugs. Although neutrophils are the primary responder to C. albicans during invasive candidiasis, biofilms resist killing by neutrophils. Prior investigation, with the commonly used laboratory strain SC5314, linked this phenotype to the impaired release of neutrophil extracellular traps (NETs), which are...
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