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Article

Evolutionary selection of a 19-stranded mitochondrial β-barrel scaffold bears structural and functional significance.

The Journal of biological chemistry - 23 Oct 2020

Srivastava Shashank Ranjan, Mahalakshmi Radhakrishnan

Abstract excerpt

Transmembrane β-barrels of eukaryotic outer mitochondrial membranes (OMMs) are major channels of communication between the cytosol and mitochondria and are indispensable for cellular homeostasis. A structurally intriguing exception to all known transmembrane β-barrels is the unique odd-stranded, i.e. 19-stranded, structures found solely in the OMM. The molecular origins of this 19-stranded structure and its...

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Identifiers

PMID: 32817169
DOI: 10.1074/jbc.RA120.014366
PMCID: PMC7586230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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