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Association of RAD51C germline mutations with breast cancer among Bahamians.

Breast cancer research and treatment - 1 Nov 2020

Bagherzadeh Maryam, Szymiczek Agata, Donenberg Talia, Butler Raleigh, Hurley Judith, Narod Steven A, Akbari Mohammad R

Abstract excerpt

PURPOSE: RAD51C is known as an ovarian cancer gene; however, its role in breast cancer susceptibility is less clear. As part of a larger study, we assessed the role of germline RAD51C mutations in breast cancer development. METHODS: We studied 387 unselected, BRCA1- and BRCA2-negative, Bahamian breast cancer cases and 653 controls to search for novel genetic associations with breast cancer development. During the...

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PMID: 32809180
DOI: 10.1007/s10549-020-05872-3

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