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Article

Isl2b regulates anterior second heart field development in zebrafish

20 Jan 2017

Abstract excerpt

After initial formation, the heart tube grows by addition of second heart field progenitor cells to its poles. The transcription factor Isl1 is expressed in the entire second heart field in mouse, and Isl1-deficient mouse embryos show defects in arterial and venous pole development. The expression of Isl1 is conserved in zebrafish cardiac progenitors; however, Isl1 is required for cardiomyocyte differentiation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28106108
DOI: 10.1038/srep41043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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