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Article

New preclinical models for angioimmunoblastic T-cell lymphoma: filling the GAP

14 Aug 2020

Abstract excerpt

Mouse models are essential to study and comprehend normal and malignant hematopoiesis. The ideal preclinical model should mimic closely the human malignancy. This means that these mice should recapitulate the clinical behavior of the human diseases such as cancer and therapeutic responses with high reproducibility. In addition, the genetic mutational status, the cell phenotype, the microenvironment of the tumor...

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PMID: 32796826
DOI: 10.1038/s41389-020-00259-x

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