Article
Construction of induced pluripotent stem cell line (ZZUi0017-A) from the fibroblast cells of a female patient with CACNA1A mutation by unintegrated reprogramming approach.
Stem cell research - 1 Oct 2020
Yang Jing, Liu Han, Sun Huifang, Wang Zhuoya, Zhang Rui, Liu Yutao, Zhang Qi, Zhang Shoutao, Zhang Jin, Shi Changhe, Wang Yanlin, Xu Yuming
Abstract excerpt
Ataxia is a common clinical symptom of neurodegenerative diseases, such as spinocerebellar ataxia, Parkinson's disease. Spinocerebellar ataxia includes more than 40 types. In clinical work, we collected the clinical data and skin tissue of one patient with SCA6 who have definitive genetic test results. More than that, we reprogrammed the patient derived fibroblast cells to induced pluripotent stem cells (iPSCs)...
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