Article
Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H196.
Stem cell research - 1 Jan 2016
Marthaler Adele G, Schmid Benjamin, Tubsuwan Alisa, Poulsen Ulla B, Hyttel Poul, Nielsen Troels T, Nielsen Jørgen E, Holst Bjørn
Abstract excerpt
Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease primarily affecting the cerebellum. Very little is known about the molecular mechanisms underlying the disease and, to date, no cure or treatment is available. Here, we demonstrate the generation of an induced pluripotent stem cell (iPSC) line of a SCA2 patient. The selected clone has been proven to be a bona fide iPSC line, which retains a...
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