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Article

Establishment of induced pluripotent stem cell line (ZZUi009-A) from an Alzheimer's disease patient carrying a PSEN1 gene mutation.

Stem cell research - 1 Mar 2018

Wang Yanlin, Jing Na, Su Linlin, Shi Changhe, Zhang Pei, Wang Zhilei, Sun Huifang, Yang Jing, Liu Yutao, Wen Xuejun, Zhang Jin, Zhang Shoutao, Xu Yuming

Abstract excerpt

Skin fibroblasts were obtained from a 42-year-old Alzheimer's disease (AD) patient carrying mutations in the PSEN1 gene. An iPSC line was successfully established using the Sendai-virus (SeV) delivery system. The patient-specific iPSCs were free of genomically integrated reprogramming genes, had the specific mutation, expressed the expected pluripotency markers, and had the potential to differentiate into cells...

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Source

Identifiers

PMID: 29304399
DOI: 10.1016/j.scr.2017.12.005

Genes

PSEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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