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Genetic and Molecular Heterogeneity of Synovial Sarcoma and Associated Challenges in Therapy

14 Oct 2024

Abstract excerpt

Synovial sarcoma (SS) is one of the most common types of pediatric soft tissue sarcoma (STS) being far less frequent in adults. This STS type is characterized by one specific chromosomal translocation SS18-SSX and the associated changes in signaling. However, other genetic and epigenetic abnormalities in SS do not necessarily include SS18-SSX-related events, but abnormalities are more sporadic and do not...

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CAR-T cell therapy research
Protein Degradation and Inhibitors
Sarcoma Diagnosis and Treatment

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39451213
DOI: 10.3390/cells13201695

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