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Article

Epigenetic Abnormalities in Chondrosarcoma

25 Feb 2023

Abstract excerpt

In recent years, our understanding of the epigenetic mechanisms involved in tumor pathology has improved greatly. DNA and histone modifications, such as methylation, demethylation, acetylation, and deacetylation, can lead to the up-regulation of oncogenic genes, as well as the suppression of tumor suppressor genes. Gene expression can also be modified on a post-transcriptional level by microRNAs that contribute...

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PMID: 36901967
DOI: 10.3390/ijms24054539

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