Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mucosal Inflammatory and Wound Healing Gene Programmes Reveal Targets for Stricturing Behaviour in Paediatric Crohn’s Disease

4 Aug 2020

Abstract excerpt

BACKGROUND AND AIMS: Ileal strictures are the major indication for resective surgery in Crohn's disease (CD). We aimed to define ileal gene programs present at diagnosis linked with future stricturing behavior during five year follow-up, and to identify potential small molecules to reverse these gene signatures. METHODS: Antimicrobial serologies and pre-treatment ileal gene expression were assessed in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune and Inflammatory Disorders
Share to Barrier Structure and Function Studies
Share to Inflammatory Bowel Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32770196
DOI: 10.1093/ecco-jcc/jjaa166

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mucosal Inflammatory and Wound Healing Gene Programmes Reveal Targets for Stricturing Behaviour in Paediatric Crohn’s DiseasePMID 32770196Read ↗

Linking Gene Expression to Clinical Outcomes in Pediatric Crohn’s Disease Using Machine LearningSemantic proximity Read ↗

Linking gene expression to clinical outcomes in pediatric Crohn’s disease using machine learningSemantic proximity Read ↗

Novel Transcriptomic Signatures in Fibrostenotic Crohn’s Disease: Dysregulated Pathways, Promising Biomarkers, and Putative Therapeutic TargetsSemantic proximity Read ↗

Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohn’s diseaseSemantic proximity Read ↗

Molecular classification of Crohn's disease reveals two clinically relevant subtypes.Semantic proximity Read ↗

Profiling Non-Coding RNA Levels With Clinical Classifiers in Pediatric Crohn’s DiseaseSemantic proximity Read ↗

Molecular Comparison of Adult and Pediatric Ulcerative Colitis Indicates Broad Similarity of Molecular Pathways in Disease TissueSemantic proximity Read ↗

Stricturing Crohn’s disease single-cell RNA sequencing reveals fibroblast heterogeneity and intercellular interactionsSemantic proximity Read ↗

Single-Cell RNA Sequencing of Terminal Ileal Biopsies Identifies Signatures of Crohn’s Disease PathogenesisSemantic proximity Read ↗

Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn DiseaseSemantic proximity Read ↗

RNA-seq Reveals Transcriptomic Differences in Inflamed and Noninflamed Intestinal Mucosa of Crohnʼs Disease Patients Compared with Normal Mucosa of Healthy ControlsSemantic proximity Read ↗

Transcriptomic analysis of ileal tissue from Crohn's disease patients identifies extracellular matrix genes that distinguish individuals by age at diagnosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.