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Article

Relationships between Chromosome 7 Gain, MET Gene Copy Number Increase and MET Protein Overexpression in Chinese Papillary Renal Cell Carcinoma Patients.

PloS one - 1 Jan 2015

Yin Xiaolu, Zhang Tianwei, Su Xinying, Ji Yan, Ye Peng, Fu Haihua, Fan Shuqiong, Shen Yanying, Gavine Paul R, Gu Yi

Abstract excerpt

To investigate the relationships between Chromosome 7 gain, mesenchymal-epithelial transition factor (MET) gene copy number increase and MET protein overexpression in Chinese patients with papillary renal cell carcinoma (PRCC), immunohistochemistry (IHC), immunofluorescence (IF) and fluorescence in situ hybridization (FISH) were performed on 98 formalin-fixed, paraffin-embedded (FFPE) PRCC samples. Correlations...

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Topics

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Share to Carcinoma, Renal Cell
Share to Chromosomes, Human, Pair 7

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Amplification

Share to Gene Expression Regulation, Neoplastic

Share to In Situ Hybridization, Fluorescence

Share to Kidney Neoplasms

Share to Proto-Oncogene Proteins c-met

Share to Up-Regulation

Source

Open in PubMed Open full text

Identifiers

PMID: 26636767
DOI: 10.1371/journal.pone.0143468
PMCID: PMC4670110

Genes

MET
PRCC

Provenance

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