MET is a potential target across all papillary renal cell carcinomas: result from a large molecular study of pRCC with CGH array and matching gene expression array.

doi:10.1158/1078-0432.CCR-13-2173

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Article

MET is a potential target across all papillary renal cell carcinomas: result from a large molecular study of pRCC with CGH array and matching gene expression array.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2014

Albiges Laurence, Guegan Justine, Le Formal Audrey, Verkarre Virginie, Rioux-Leclercq Nathalie, Sibony Mathilde, Bernhard Jean-Christophe, Camparo Philippe, Merabet Zahira, Molinie Vincent, Allory Yves, Orear Cedric, Couvé Sophie, Gad Sophie, Patard Jean-Jacques, Escudier Bernard

Abstract excerpt

PURPOSE: Papillary renal cell carcinomas (pRCC) are the most common nonclear cell RCC subtype. Germline mutations of the MET oncogene at 7q31 have been detected in patients with hereditary type I pRCC and in 13% of sporadic type I pRCC. Recent report of MET inhibition strengthened the role of c-Met inhibition across pRCC. EXPERIMENTAL DESIGN: We collected 220 frozen samples of sporadic pRCC through the French RCC...

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PMID: 24658158
DOI: 10.1158/1078-0432.CCR-13-2173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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