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A genome-wide analysis of multidrug-resistant and extensively drug-resistant strains of Mycobacterium tuberculosis Beijing genotype.

Molecular genetics and genomics : MGG - 1 Sept 2013

Wu Wei, Zheng Huajun, Zhang Lu, Wen Zilu, Zhang Shulin, Pei Hao, Yu Guohua, Zhu Yongqiang, Cui Zhenling, Hu Zhongyi, Wang Honghai, Li Yao

Abstract excerpt

The Beijing genotype of Mycobacterium tuberculosis (MTB) is one of the most successful MTB lineages that has disseminated in the world. In China, the rate of multidrug-resistant (MDR) tuberculosis is significantly higher than the global average rate, and the Beijing genotype strains take the largest share of MDR strains. To study the genetic basis of the epidemiological findings that Beijing genotype has often...

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PMID: 23801408
DOI: 10.1007/s00438-013-0758-4

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