Article
Whole genome analysis of an MDR Beijing/W strain of Mycobacterium tuberculosis with large genomic deletions associated with resistance to isoniazid.
Gene - 15 May 2016
Zhang Qiufen, Wan Baoshan, Zhou Aiping, Ni Jinjing, Xu Zhihong, Li Shuxian, Tao Jing, Yao YuFeng
Abstract excerpt
Mycobacterium tuberculosis (M.tb) is one of the most prevalent bacterial pathogens in the world. With geographical wide spread and hypervirulence, Beijing/W family is the most successful M.tb lineage. China is a country of high tuberculosis (TB) and high multiple drug-resistant TB (MDR-TB) burden, and the Beijing/W family strains take the largest share of MDR strains. To study the genetic basis of Beijing/W...
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