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Article

Effect of functional variant rs11466313 on breast cancer susceptibility and TGFB1 promoter activity.

Breast cancer research and treatment - 1 Nov 2020

Zhou Yan-Ting, Zheng Li-Yuan, Wang Ya-Jun, Yang Li, Xie Yun-Tao, Panda Ipsita, Tian Xin-Xia, Fang Wei-Gang

Abstract excerpt

PURPOSE: This study aimed to investigate whether genetic polymorphisms in TGFB1 contribute to breast cancer (BC) susceptibility, and explore the mechanism of action. METHODS: A total of 7 tagging SNPs (tSNPs) were genotyped in 1161 BC cases and 1337 age-matched controls among Chinese Han population. Bioinformatics analysis was used to predict functional SNP closely linked to tSNPs. Luciferase gene reporter assay...

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PMID: 32757134
DOI: 10.1007/s10549-020-05841-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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