Article
Interplay Between Statins, Cav1 (Caveolin-1), and Aldosterone.
Hypertension (Dallas, Tex. : 1979) - 1 Sept 2020
Haas Andrea V, Baudrand Rene, Easly Rebecca M, Murray Gillian R, Touyz Rhian M, Pojoga Luminita H, Jeunemaitre Xavier, Hopkins Paul N, Rosner Bernard, Williams Jonathan S, Williams Gordon H, Adler Gail K
Abstract excerpt
Statin use is associated with lower aldosterone levels. We hypothesized that caveolin-1 may be important for the uptake of statins into the adrenal gland and would affect statin's aldosterone-lowering effects. The aim of this study was to test whether the caveolin-1 risk allele (rs926198) would affect aldosterone levels associated with statin use. The Hypertensive Pathotype database includes healthy and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.