Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis.

Journal of the American Heart Association - 28 Sept 2016

Baudrand Rene, Gupta Nidhi, Garza Amanda E, Vaidya Anand, Leopold Jane A, Hopkins Paul N, Jeunemaitre Xavier, Ferri Claudio, Romero Jose R, Williams Jonathan, Loscalzo Joseph, Adler Gail K, Williams Gordon H, Pojoga Luminita H

Abstract excerpt

BACKGROUND: Overactivation of the aldosterone and mineralocorticoid receptor (MR) pathway is associated with hyperglycemia and dyslipidemia. Caveolin 1 (cav-1) is involved in glucose/lipid homeostasis and may modulate MR signaling. We investigated the interplay between cav-1 and aldosterone signaling in modulating insulin resistance and dyslipidemia in cav-1-null mice and humans with a prevalent variant in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aldehyde Reductase
Share to Aldosterone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caveolin 1

Share to Dyslipidemias

Share to Hypertriglyceridemia

Share to Receptors, Mineralocorticoid

Share to Resistin

Share to Retinol-Binding Proteins, Plasma

Source

Open in PubMed Open full text

Identifiers

PMID: 27680666
DOI: 10.1161/JAHA.116.003845
PMCID: PMC5121487

Genes

CAV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis.PMID 27680666Read ↗

Variants of the caveolin-1 gene: a translational investigation linking insulin resistance and hypertension.Semantic proximity Read ↗

Are Caveolin-1 minor alleles more likely to be risk alleles in IR mechanisms in metabolic diseases?Semantic proximity Read ↗

Are caveolin-1 minor alleles more likely to be risk alleles in insulin resistance mechanisms in metabolic diseases?Semantic proximity Read ↗

Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities.Semantic proximity Read ↗

Interplay Between Statins, Cav1 (Caveolin-1), and Aldosterone.Semantic proximity Read ↗

Caveolin-1 genetic polymorphism interacts with PUFA to modulate metabolic syndrome risk.Semantic proximity Read ↗

Distinct roles of endothelial and adipocyte caveolin-1 in macrophage infiltration and adipose tissue metabolic activity.Semantic proximity Read ↗

Beclin-1 restrains aldosterone signaling via autophagic degradation of the mineralocorticoid receptor to protect against cardiovascular injurySemantic proximity Read ↗

Regulation of NO Synthesis by Caveolin-1: A Review of Its Importance in Blood Vessels, Perivascular Adipose Tissue and in AtherosclerosisSemantic proximity Read ↗

A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics.Semantic proximity Read ↗

Lessons from cavin-1 deficiency.Semantic proximity Read ↗

Sex-Specific Mechanisms of Resistance Vessel Endothelial Dysfunction Induced by Cardiometabolic Risk Factors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.