Article
KCNJ5 Somatic Mutations in Aldosterone-Producing Adenoma Are Associated With a Worse Baseline Status and Better Recovery of Left Ventricular Remodeling and Diastolic Function.
Hypertension (Dallas, Tex. : 1979) - 1 Jan 2021
Chang Yi-Yao, Tsai Cheng-Hsuan, Peng Shih-Yuan, Chen Zheng-Wei, Chang Chin-Chen, Lee Bo-Ching, Liao Che-Wei, Pan Chien-Ting, Chen Ya-Li, Lin Lung-Chun, Chang Yi-Ru, Peng Kang-Yung, Chou Chia-Hung, Wu Vin-Cent, Hung Chi-Sheng, Lin Yen-Hung
Abstract excerpt
Primary aldosteronism is the most common secondary endocrine form of hypertension and causes many cardiovascular injuries. KCNJ5 somatic mutations have recently been identified in aldosterone-producing adenoma. However, their impacts on left ventricular remodeling precluding the interference of age, sex, and blood pressure are still uncertain. We enrolled 184 aldosterone-producing adenoma patients who received...
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