Article
TLR4 896A/G and TLR9 1174G/A polymorphisms are associated with the risk of infectious mononucleosis.
Scientific reports - 4 Aug 2020
Jabłońska Agnieszka, Studzińska Mirosława, Szenborn Leszek, Wiśniewska-Ligier Małgorzata, Karlikowska-Skwarnik Monika, Gęsicki Tomasz, Paradowska Edyta
Abstract excerpt
Toll-like receptors (TLRs) recognize pathogen-associated molecular patterns and activate innate and adaptive immune responses. Single nucleotide polymorphisms (SNPs) within the TLR genes may influence host-pathogen interactions and can have an impact on the progression of infectious diseases. The present study aimed to investigate the genotype distribution of TLR2 (2029C/T, rs121917864; 2258G/A, rs5743708), TLR4...
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