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Article

Toll-like receptor gene polymorphisms in patients with myeloproliferative neoplasms.

Molecular biology reports - 1 Jun 2021

Quirino Marília Gonçalves, Macedo Luciana Conci, Pagnano Katia Borgia Barbosa, Pagliarini-E-Silva Sarah, Sell Ana Maria, Visentainer Jeane Eliete Laguila

Abstract excerpt

Toll-like receptors (TLRs) are a family of transmembrane receptors whose signaling control cellular processes of cell proliferation, survival, apoptosis, angiogenesis, remodeling, and repair of tissues. Polymorphisms in TLR genes can change the balance between pro and anti-inflammatory cytokines, modulating the risk of infection, chronic inflammation, and cancer. Although many studies have demonstrated the direct...

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Identifiers

PMID: 34191235
DOI: 10.1007/s11033-021-06238-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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