Article
A genome-wide scan for candidate lethal variants in Thoroughbred horses.
Scientific reports - 4 Aug 2020
Todd Evelyn T, Thomson Peter C, Hamilton Natasha A, Ang Rachel A, Lindgren Gabriella, Viklund Åsa, Eriksson Susanne, Mikko Sofia, Strand Eric, Velie Brandon D
Abstract excerpt
Domestic animal populations are often characterised by high rates of inbreeding and low effective population sizes due to selective breeding practices. These practices can result in otherwise rare recessive deleterious alleles drifting to high frequencies, resulting in reduced fertility rates. This study aimed to identify potential recessive lethal haplotypes in the Thoroughbred horse breed, a closed population...
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