Article
Genome-Wide Assessment of Runs of Homozygosity by Whole-Genome Sequencing in Diverse Horse Breeds Worldwide.
Genes - 1 Jun 2023
Chen Chujie, Zhu Bo, Tang Xiangwei, Chen Bin, Liu Mei, Gao Ning, Li Sheng, Gu Jingjing
Abstract excerpt
In the genomes of diploid organisms, runs of homozygosity (ROH), consecutive segments of homozygosity, are extended. ROH can be applied to evaluate the inbreeding situation of individuals without pedigree data and to detect selective signatures via ROH islands. We sequenced and analyzed data derived from the whole-genome sequencing of 97 horses, investigated the distribution of genome-wide ROH patterns, and...
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