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Article

Innovative HBV Animal Models Based on the Entry Receptor NTCP

30 Jul 2020

Abstract excerpt

Hepatitis B is a major global health problem, with an estimated 257 million chronically infected patients and almost 1 million deaths per year. The causative agent is hepatitis B virus (HBV), a small, enveloped, partially double-stranded DNA virus. HBV has a strict species specificity, naturally infecting only humans and chimpanzees. Sodium taurocholate co-transporting polypeptide (NTCP), a bile acid transporter...

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PMID: 32751581
DOI: 10.3390/v12080828

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