Article
NTCP and beyond: opening the door to unveil hepatitis B virus entry.
International journal of molecular sciences - 19 Feb 2014
Watashi Koichi, Urban Stephan, Li Wenhui, Wakita Takaji
Abstract excerpt
Chronic hepatitis B virus (HBV) infection, affecting approximately 240 million people worldwide, is a major public health problem that elevates the risk of developing liver cirrhosis and hepatocellular carcinoma. Given that current anti-HBV drugs are limited to interferon-based regimens and nucleos(t)ide analogs, the development of new anti-HBV agents is urgently needed. The viral entry process is generally an...
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